sexta-feira, 25 de junho de 2010

Humani corporis fabrica

De Humani Corporis Fabrica Libri Septem ou simplesmente De Humani Corporis Fabrica (Da Organização do Corpo Humano) é um livro de anatomia humana, escrito por Andreas Vesalius em 1543. Considerado um dos mais influentes livros científicos de todos os tempos, De Humanis Corporis Fabrica é conhecido sobretudo por suas ilustrações, algumas das mais perfeitas xilogravuras jamais realizadas.


Melhor que estudar em figuras é observar as peças preparadas pelo técnica inovadora de dissecção humana pelo grupo de Pequim.


Os corpos passam por um tratamento que leva cerca de um ano e meio e envolve acetona e silicone líquido, que é enrijecido para simular o tônus natural. Depois disso, cada músculo é pintado cuidadosamente com os tons que ostentavam quando seus donos ainda estavam vivos.


Para download do livro de Vesalius...
http://www.divshare.com/download/11812808-34f

Estudo penta cego

Dependência pela internet

Fisiologia aplicada em terapia intensiva: livro

Fisiologia aplicada em terapia intensiva


download: http://www.divshare.com/download/11811695-38d

Transfusion Medicine: Livro


Transfusion medicine: a clinical guide

Livro de boa leitura e rápida sobre o assunto.

Download:  http://www.divshare.com/download/11811696-560

Sugammadex

Sugammadex: Another Milestone in Clinical Neuromuscular Pharmacology


Sugammadex is a revolutionary investigational reversal drug currently undergoing Phase III testing whose introduction into clinical practice may change the face of clinical neuromuscular pharmacology. A modified -cyclodextrin, sugammadex exerts its effect by forming very tight water-soluble complexes at a 1:1 ratio with steroidal neuromuscular blocking drugs (rocuronium vecuronium pancuronium). During rocuronium-induced neuromuscular blockade, the IV administration of sugammadex creates a concentration gradient favoring the movement of rocuronium molecules from the neuromuscular junction back into the plasma, which results in
a fast recovery of neuromuscular function. Sugammadex is biologically inactive, does not bind to plasma proteins, and appears to be safe and well tolerated.
Additionally, it has no effect on acetylcholinesterase or any receptor system in the body. The compound’s efficacy as an antagonist does not appear to rely on renal excretion of the cyclodextrin-relaxant complex. Human and animal studies have demonstrated that sugammadex can reverse very deep neuromuscular blockade induced by rocuronium without muscle weakness. Its future clinical use should decrease the incidence of postoperative muscle weakness, and thus contribute to increased patient safety.
Sugammadex will also facilitate the use of rocuronium for rapid sequence induction of anesthesia by providing a faster onset-offset profile than that seen with 1.0 mg/kg succinylcholine. Furthermore, no additional anticholinesterase or anticholinergic drugs would be needed for antagonism of residual neuromuscular blockade, which would mean the end of the cardiovascular and other side effects of these compounds. The clinical use of sugammadex promises to eliminate many of the shortcomings in our current practice
with regard to the antagonism of rocuronium and possibly other steroidal neuromuscular blockers.


Anesthesia e analgesia
Vol. 104, No. 3, March 2007

Download: http://www.divshare.com/download/11811693-50d

Goodbye Suxamethonium!

No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as
suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For
decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an
encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients.
With the arrival of sugammadex, it finally appears that suxamethonium can be retired. Suxamethonium
has done its job and seen its days! The present review is intended to offer a eulogy for
suxamethonium.

C. Lee

Anaesthesia, 2009, 64 (Suppl. 1), pages 73–81

download http://www.divshare.com/download/11811692-c8a

Achei o anestesiador on Twitpic


Achei o anestesiador on Twitpic

Grande dupla! @anestesiador e @gustavoolivetti;

Bo,s tempos no corredor do INCOR há 13 anos....

Olha o @anestesiador brilhando no COPA on Twitpic


Olha o @anestesiador no COPA on Twitpic

Aula: Risco de broncoaspiração pulmonar no obeso!

@anestesiador e Sra(anestesiadora) no burburinho do COPA on Twitpic


@anestesiador e Sra(anestesiadora) no burburinho do COPA on Twitpic

Na festa do Congresso Pauslita de Anestesiologia
 2010!