No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as
suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For
decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an
encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients.
With the arrival of sugammadex, it finally appears that suxamethonium can be retired. Suxamethonium
has done its job and seen its days! The present review is intended to offer a eulogy for
suxamethonium.
C. Lee
Anaesthesia, 2009, 64 (Suppl. 1), pages 73–81
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